- Travel to the Shrine to Peryite
Once you have reached the required level, traveling around Skyrim may net you a random encounter with a sickly looking Afflicted Refugee, who ask you to stop “ogling the grotesque.” Seemingly ill and tired of fighting, he will gladly stop to talk. When asked about his worrying skin condition, he will say he suffers from the plague and would have been dead years ago without Peryite’s protection. Eager to get back to High Rock, he will point you to Kesh at the Shrine to Peryite for more information, adding a miscellaneous quest to your journal. The shrine is located in The Reach, far to the northeast of Markarth, a little southwest of the Dragontooth Crater landmark.
This quest serves as a pointer to the quest The Only Cure.